![]() ![]() Similar to honokiol, studies in animals have shown that magnolol may help control and suppress tumor growth in various organs. What’s more, magnolol likewise appears to have anticancer properties. Though more rigorous human studies are needed, the polyphenol shows promise as an anticancer therapy in humans ( 20). Given that cancer is a disease characterized by abnormal cell division and growth, the ability to regulate cellular pathways is beneficial ( 16).Ī 2019 review study found that honokiol has shown potential to prevent tumor growth in the brain, breast, colon, liver, and skin, among other organs ( 17).įurthermore, honokiol may not only have anticancer properties itself but also help increase the effectiveness of other anticancer and radiation drug therapies ( 18, 19). One way in which honokiol may combat cancer is by helping regulate cell signaling pathways. Various studies on honokiol support the use of this polyphenol in magnolia bark as a therapy for cancer treatment and prevention. Nevertheless, additional research in humans is needed. In a 2016 review, magnolia bark was found to improve high blood sugar levels and diabetic complications in animals ( 15). Moreover, oxidative stress is widely believed to contribute to diabetes and its related complications. ![]() This suggests that it has potential as a therapeutic agent for neurodegenerative diseases like Alzheimer’s. Research on honokiol has found that it can reduce inflammation in the brain and spinal cord specifically, partly due to its ability to cross the blood-brain barrier ( 14). In research, changes in levels of methane dicarboxylic aldehyde are often interpreted as a sign of antioxidant activity. Polyphenols, such as those found in magnolia bark, have been suggested as a potential therapy to combat the side effects of oxidative stress and inflammation ( 12).īased on research in mice, some scientists believe that honokiol may help combat aging by increasing antioxidant enzymes and decreasing levels of methane dicarboxylic aldehyde ( 13). Oxidative stress also appears to play a significant role in many changes in the body and mind that accompany aging ( 11). Oxidative stress and subsequent inflammation are one cause of chronic conditions like diabetes, cancer, heart disease, and neurodegenerative diseases like Alzheimer’s ( 9, 10). May protect against the effects of oxidative stress and inflammation Here is a closer look at some of the potential benefits of magnolia bark. It’s important to note that the exact mechanisms through which the isolated compounds contribute to these effects are still being investigated. These compounds, including magnolol and honokiol, have been studied extensively in recent years for their anti-inflammatory, anticancer, antimicrobial, and antioxidant benefits ( 1, 2, 4, 6, 7, 8). Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.Aside from neolignans, more than 200 chemical compounds have been isolated from the tree ( 5). Please check with the appropriate physician regarding health questions and concerns. The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. International Journal of Molecular Medicine Beneficial Effect of Flos Magnoliae Extract.Chinese Journal of Integrated Traditional and Western Medicine" los Magnoliae Volatile Oil Nano-liposome Nasal Drops in Treating Pediatric Allergic Rhinitis M.International Archives of Allergy and Immunology Magnoliae Flos.The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data. Our team periodically reviews articles in order to ensure content quality. At Healthfully, we strive to deliver objective content that is accurate and up-to-date.
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